Survival-associated meQTLs across different cancer types
We identified 23,432 meQTLs associated with patient overall survival across different cancer types at FDR < 0.05.
|
Cancer type
|
SNP ID
|
SNP position (hg19)
|
Alleles (A/a)
|
log-rank test p-value
|
Sample size
|
Median survival time AA
|
Median survival time Aa
|
Median survival time aa
|
|
|---|---|---|---|---|---|---|---|---|---|
| BLCA | rs77096391 | chr16:70923738 | C/T | 1.98E-7 | 397 | 17.23 | 20.5 | 3.9 | KM Plot |
| BLCA | rs7736284 | chr5:131588151 | T/C | 3.36E-6 | 399 | 21.37 | 17.87 | 14.37 | KM Plot |
| BLCA | rs77474078 | chr13:25857527 | G/A | 1.18E-12 | 402 | 17.77 | 18.62 | 4.97 | KM Plot |
| BLCA | rs77766065 | chr13:25846830 | C/T | 2.13E-8 | 402 | 17.87 | 16.93 | 5.13 | KM Plot |
| BLCA | rs77839004 | chr13:25838252 | A/G | 4.1E-8 | 404 | 17.87 | 17.53 | 5.13 | KM Plot |
| BLCA | rs78160478 | chr16:2107322 | G/T | 3.75E-6 | 398 | 17.4 | 24.3 | 6.83 | KM Plot |
| BLCA | rs79068065 | chr13:25847581 | T/A | 2.19E-8 | 402 | 17.77 | 18.13 | 5.13 | KM Plot |
| BLCA | rs79456230 | chr2:114455354 | TA/T | 2.54E-5 | 387 | 18 | 16.4 | 7.03 | KM Plot |
| BLCA | rs8017258 | chr14:66231017 | C/G | 2.03E-5 | 405 | 16.97 | 19.07 | 4.27 | KM Plot |
| BLCA | rs81598 | chr5:131587960 | C/G | 9.22E-6 | 399 | 18.62 | 19.45 | 14.27 | KM Plot |
| BLCA | rs932019 | chr5:131599370 | T/C | 1.84E-6 | 400 | 18.62 | 19.1 | 14.47 | KM Plot |
| BLCA | rs9456678 | chr6:161918092 | C/T | 4.73E-11 | 405 | 17.47 | 18.23 | 2.27 | KM Plot |
| BRCA | rs10505989 | chr12:26213449 | G/A | 4.14E-6 | 1059 | 28.63 | 25.88 | 23.63 | KM Plot |
| BRCA | rs11346691 | chr20:25119259 | AT/A | 2.64E-6 | 1081 | 28.72 | 29.78 | 15.67 | KM Plot |
| BRCA | rs117210448 | chr7:112095254 | G/A | 1.97E-6 | 1078 | 27.97 | 28.3 | 26.4 | KM Plot |